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New tool activates deep brain neurons by combining ultrasound, genetics

New tool activates deep brain neurons by combining ultrasound, genetics | healthcare technology | Scoop.it

Neurological disorders such as Parkinson's disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation.

 

A multidisciplinary team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.

 

The team, led by Hong Chen, is the first to provide direct evidence showing noninvasive, cell-type-specific activation of neurons in the brain of mammal by combining ultrasound-induced heating effect and genetics, which they have named sonothermogenetics.

 

It is also the first work to show that the ultrasound- genetics combination can robustly control behavior by stimulating a specific target deep in the brain.

 

Results of the three years of research, which was funded in part by the National Institutes of Health's BRAIN Initiative, were published online in Brain Stimulation May 11, 2021.

 

"Our work provided evidence that sonothermogenetics evokes behavioral responses in freely moving mice while targeting a deep brain site," Chen said. "Sonothermogenetics has the potential to transform our approaches for neuroscience research and uncover new methods to understand and treat human brain disorders."

 

 

more at https://medicalxpress.com/news/2021-05-tool-deep-brain-neurons-combining.html

 

 

Nassima Chraibi's curator insight, January 9, 2023 12:07 PM
This article discusses a new non-invasive deep brain stimulation technique, called sonothermogenetics, which allows to precisely target certain types of neurons. This new technique could allow the development of new methods and research on brain disorders.
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Nationwide ‘Paperless’ eHealth project Commenced in Ghana

The Ministry of Health and the Ghana Health Service has engaged the services of Lightwave ehealthcare Services (LWEHS) to roll out an integrated health care solution that includes a Centralized data center with a 24 hour recovery unit to serve as an infrastructure platform for a patient-centered health care solution.

 

The solution will network all health facilities including agencies of the Ministry of Health, provide electronic Medical records for care seekers, enable and facilitate tele medicine, and develop a a real time bio-surveillance system – which will support the fight against disease outbreaks and the spread of communicable disease.

 

The system which integrates with the current National Health Insurance Scheme (NHIS) enables the development of a patient management system – this will streamline the Admission, discharge and transfer process of healthcare.

 

Chief Technology Officer of Lightwave Mr Thomas Mac Scofield, said the project was a culmination of years of planning and working with the MOH to bring ehealth solutions to the public health care industry.

 

Mr Thomas Mac Scofield revealed to Ghanahealthnest.com that, the cost of the project is covered by the government through the MoH and GHS thus will not require patients or subscribers to pay for it.

 

Nrip Nihalani consulting director with LightWave revealed to Ghanahealthnest.com that the project follows Ghana’s Data privacy and HIPAA laws to ensure its safety.

 

He added that, the time was right for Ghana as most countries have gone ahead and made significant mistakes. “Ghana is at the absolute time with the technologies, the budgets, the preparedness all meeting together to launch its e-health”, Nrip intoned.

 

more at : http://ghanahealthnest.com/nationwide-paperless-ehealth-project-commenced-ghana/

 

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